Tamoxifen Side Effects

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What is Tamoxifen?

Tamoxifen is a hormone therapy drug used for the prevention and treatment of breast cancer.

Tamoxifen has been approved by the FDA to reduce the risk of developing breast cancer in women at high risk of the disease. Tamoxifen is also used to treat all stages of hormone receptor-positive breast cancer.

Board-Certified Surgeon

MICHELE LEY, MD, FACS

Dr. Ley, a breast surgical oncologist in Tucson since 2006, delivers compassionate and personalized care to create tailored treatment plans based on the latest research. Specializing in surgical care for breast cancer and high-risk patients, she employs minimally invasive techniques and practices oncoplastic surgery to optimize outcomes.

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This medication works by blocking the effects of estrogen on hormone receptor-positive breast cancer cells by staying in the estrogen receptors on the cells. If Tamoxifen is in the receptor, estrogen cannot attach to the cancer cell, and the cell will not receive the signals and grow and multiply. Tamoxifen will not work on hormone receptor-negative breast cancer.

Medicines to Avoid with Tamoxifen

While taking Tamoxifen, you should not take medications that are moderate to strong CYP2D6 inhibitors. This is because they decrease the effect of Tamoxifen. Many antidepressants are CYP2D6 inhibitors, but some are not, so be sure to discuss your current medication list with your doctor.

“The level of care is excellent.”

Dr. Ley is an excellent doctor who cares about her patients. She takes the time to explain everything and provides all options. The level of care is excellent.

When diagnosed with Breast Cancer my daughter, which is a surgical nurse, started searching for a breast surgeon for me. Within a short period of time, she called stating “Mom, Dr Ley is the surgeon for you”! I have not been disappointed & have had nothing but positive experiences with Dr. Ley & her staff. They truly care.

Tamoxifen Side Effects

Common side effects of Tamoxifen include:

  • Hot flashes
  • Night sweats
  • Nausea
  • Mood swings
  • Depression
  • Vaginal discharge
  • Disruption of the menstrual cycle
  • Loss of libido
  • Constipation
  • Hair thinning

Less common but serious side effects of Tamoxifen include:

To learn more about tamoxifen and its side effects, click the link to ChemoCare’s Tamoxifen page here.

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If you have any questions or concerns regarding Tamoxifen, please do not hesitate to reach out to Tucson Breast Health Specialists in Tucson, AZ today. We are dedicated to helping you through each phase of your breast health journey.

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